(Gataullina, Dulac 2016). This review of current knowledge confirmed the general consensus about what Dravet syndrome entails including temperature-related seizure triggers (acknowledging pertussis vaccination as a cause of hyperthermia), status seizures, seizures in sleep as patients age, crouch gait, intellectual disability, and SUDEP susceptibility. The most noteworthy conclusions, however, included questioning whether chronic use of benzodiazepines is the best treatment for Dravet and noting that due to the effects of SCN1A mutations on several different types of neurons and systems (not just the inhibitory neurons studied in seizures), Dravet should be considered a disease rather than an epileptic syndrome.

Gataullina, S., Dulac, O. (2016). From genotype to phenotype in Dravet disease. Seizure Oct 21. Pii S1059-1311(16)30182-0. Doi: 10.1016/j.seizure.2016.10.014. http://www.sciencedirect.com/science/article/pii/S1059131116301820