Research Review2019-05-09T15:56:37-05:00

DSF Research Review

Welcome to DSF’s Research Review! We use this space to keep you up to date on the most exciting studies that are published each month on Dravet syndrome and SCN1A. Each review includes a link to the original abstract or article (where possible), as well as a lay-person’s summary. Have questions? Email our team.

Looking for more information on research? Click on the button below to go to a list of pubmed published scientific articles on Dravet syndrome.

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June 2019

May 2019

Efficacy and tolerability of perampanel in pediatric patients with Dravet syndrome.

By |May 9th, 2019|Categories: DSF Research Review|Tags: , , , , , |

This is a survey of the efficacy of perampanel as an add-on therapy in children with Dravet syndrome. Perampanel (a.k.a. Fycompa) was first approved in 2012, and last year its use was extended [...]

Mitochondrial regulation of the hippocampal firing rate set point and seizure susceptibility.

By |May 9th, 2019|Categories: DSF Research Review|Tags: , , , , , , , , , , |

When the human genome was sequenced in 2000, it was hoped it would simplify the search for medicines - just compare the genome of someone with a disease to the healthy standard, identify [...]

Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results

By |May 9th, 2019|Categories: DSF Research Review|Tags: , , , , , , |

A number of publications have appeared recently reporting on the efficacy and safety of cannabidiol (CBD) as an add-on therapy, as its clinical trials are concluding and its use is extending.  This paper [...]

October 2018