Efficacy of stiripentol in Dravet syndrome with or without SCN1A mutations
(Cho et al. 2017) This small study of 32 patients with clinically-diagnosed Dravet syndrome sought to determine whether stiripentol's efficacy differed among those with and without SCN1A mutations. 15 patients had definite SCN1A mutations, and 17 had variants of unknown significance or benign variants. The severity of DS did not differ significantly between the two groups. Stiripentol [...]