Lemonade for Logan

By |2016-11-16T15:49:51+00:00September 16th, 2016|Categories: Making a Difference|

Great friends of Logan's family, the Seabolt's hosted a lemonade stand called "Lemonade for Logan". In just a few hours of hard work selling cookies and lemonade, these 4 amazing kids raised $630 for the Dravet Syndrome Foundation to help find a cure for Logan and other kids battling Dravet syndrome and Epilepsy. A big thank you to [...]

Temperature effects on the sodium ion channel

By |2016-11-03T15:08:04+00:00September 1st, 2016|Categories: DSF Research Review|

Peters, C. et al. Temperature-dependent changes in neuronal dynamics in a patient with an SCN1A mutation and hyperthermia induced seizures. It is well documented that cells with SCN1A mutations exhibit abnormal electrical activity when subjected to increased temperature. This activity can sometimes be described as loss of function, and sometimes it can be described as gain of function. This study [...]

Stiripentol in a French Cohort

By |2016-11-03T15:09:12+00:00September 1st, 2016|Categories: DSF Research Review|

De Liso, P., et. al. (Sept 2016). Patients with Dravet syndrome in the era of stiripentol: A French cohort cross-sectional study. Because stiripentol is approved for use in Europe, it is has been prescribed more regularly there than in the US (particularly in France) since the 1990s. Looking at the medical records of 54 patients [...]