Research Articles on Dravet Syndrome

Feb 2013 W. Ma, J. Berg, and G. Yellen: Ketogenic Diet Metabolites Reduce Firing in Central Neurons by Opening KATP Channels
Feb 2013 A. Bender, H. Natola, G. Holmes, R. Scott, P. Lenck-Santini: Focal Scn1a knockdown induces cognitive impairment without seizures
Nov 2012 I. Ohmoria, M. Ouchidab, K. Kobayashic, Y. Jitsumorib, A. Moria, H. Michiuea, T. Nishikia, Y. Ohtsukac, H. Matsuia: CACNA1A variants may modify the epileptic phenotype of Dravet syndrome
Nov 2012 H. Greiner, P. Horn, K. Holland, J. Collins, A. Hershey, T. Glauser: mRNA blood expression patterns in new-onset idiopathic pediatric epilepsy
Mar 2012 David N. Ruskin and Susan A. Masino: The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy
Feb 2012 F Nicita MD, G Ragusa MD, L Papetti MD, F Ursitti, M Duse MD, Al Spalice MD, PhD: The sodium channel α1 subunit (SCN1A)-related epileptic phenotypes
Nov 2011 Pierre Genton, Reana Velizarova, and Charlotte Dravet: Dravet syndrome: The long-term outcome
Oct 2010 Sooky Koh, MD, PhD: Novel Therapies to Block Epileptogenesis in Dravet Syndrome Mice
Oct 2009 Jack Parent, MD: Using Induced Pluripotent Stem Cells (iPSCs) to Study Ion Channel Mutations that Cause Dravet Syndrome
Sept 2009 Elson So, MD: Editorial on Sudden Unexplained Death in Epilepsy (SUDEP)
Oct 2009 Andrew Escagy, PhD: Genetics Based Research on Treatment Resistant Epilepsy

News on Dravet syndrome and related epilepsies

May 2013 azom.com: Imaging of Absorption Signals and Fluorescence for the Treatment of Epilepsy
May 2013 futurity.org: Epilepsy belt alerts caregivers of kid’s seizure
May 2013 ScienceDaily.com: Gene identified for SUDEP (Sudden Unexpected Death in Epilepsy)
: UK pharma firm launches oral liquid suspension of clobazam
May 2013 uanews.org: UA Geneticists find causes for severe childhood epilepsies
May 2013 newswire.com: Epilepsy cured in mice using brain cells
May 2013 newscientist.com: Brain implant gives early warning of epileptic seizures
Apr 2013 fda.gov: Epilepsy drug Potiga (ezogabine) linked to skin and eye abnormalities
Apr 2013 medscape.com: Curing Epilepsies: NIH Conference Examines State of the Art
Apr 2013 NewsMedical.net: Study examines developmental delays in children within six weeks of CSE
Apr 2013 wiley.com: Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)
Apr 2013 dailyrx.com: Prolonged seizures in children linked to developmental problems
Mar 2013 jci.org: Sudden death in epilepsy: of mice and men
Feb 2013 catholic.org: Research into epilepsy uncovers secrets of memory
Feb 2013 dailyrx.com: Poor memory in children with epilepsy linked to lower health related quality of life
Feb 2013 prnewswire.com: Researchers study bed alarms for nocturnal seizures
Feb 2013 ScienceDaily.com: Potential treatment prevents damage from prolonged seizures
Feb 2013 wiley.com: Detection of generalized tonic–clonic seizures by a wireless wrist accelerometer: A prospective, multicenter study
Feb 2013 epilepsyresearch.org.uk: Gene atlas promises future neurological breakthroughs
Feb 2013 epilepsy.com: Long-term home monitoring of seizures by patient-worn accelerometer devices
Feb 2013 pediatricnews.com: Antiepileptic meds impact kids’ Vitamin D levels
Feb 2013 news-medical.net: Look for narrative ability in children with epilepsy
Jan 2013 wsj.com: Scientists cast light onto roots of illness deep in the brain
Jan 2013 medicalexpress.com: Less tau reduces seizures and sudden death in severe epilepsy
Feb 2013 usnews.com: Study links epilepsy drug in pregnancy to lower IQ
Dec 2012 NewsMedical.net: Ion channel acts as powerful ‘brake’ after epileptic seizures
Dec 2012 natmonitor.com: Ketogenic diet and fasting may benefit children with epilepsy, say researchers
Dec 2012 modernmedicine.com: Pediatricians lack knowledge about epilepsy
Dec 2012 ScienceDaily.com: Fasting may benefit patients with epilepsy
Dec 2012 bmj.com: The impact of benzodiazepines on occurrence of pneumonia and mortality from pneumonia
Dec 2012 ScienceDaily.com: First long-term follow-up study of its kind suggests not all prolonged seizures have a poor outcome
Dec 2012 pubmed.gov: Non-truncating SCN1A mutations associated with Severe Myoclonic Epilepsy of Infancy impair cell surface expression
Nov 2012 eurekalert.org: Discovery offers new treatment for epilepsy
Nov 2012 latimes.com: Researchers use light to turn off epileptic seizures
Nov 2012 bbc.co.uk: ‘Calm down’ genes treat epilepsy in rats
Nov 2012 sciencedirect.com: Helping families cope with the devastation of Dravet syndrome
Nov 2012 channelopathist.net: CACNA1A Variants as genetic modifiers in Dravet syndrome
Nov 2012 pubmed.gov: Super-refractory status epilepticus: treatment with ketogenic diet in pediatrics
Nov 2012 ScienceDaily.com: New fruit fly model of epilepsy reveals mechanisms behind fever-induced seizures
Nov 2012 aesnet.org: SCN1A mutations in a population of children with status epilepticus
Nov 2012 aesnet.org: Dravet Syndrome: Effect of different SCN1A mutations in seizure control and gait in adults
Oct 2012 nature.com: An integrated map of genetic variation from 1,092 human genomes
Oct 2012 wiley.com: Dravet syndrome and SCN1A gene mutation related-epilepsies: cognitive impairment and its determinants
Oct 2012 wiley.com: Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: A prospective pilot study
Oct 2012 adisonline.com: Stiripentol: In Severe Myoclonic Epilepsy of Infancy (Dravet Syndrome)
Oct 2012 epilepsyresearch.org.uk: Children’s seizures ‘often dealt with inappropriately’
Sept 2012 redorbit.com: Scientists show biological mechanism can trigger epileptic seizures
Sept 2012 medicaldaily.com: Study finds that marijuana may lessen severity of epileptic seizures
Sept 2012 cbsnews.com: Kids with neurological disorders such as epilepsy may be more likely to die during flu season
Sept 2012 psychcentral.com: New scan a ‘Paradigm Shift’ in epilepsy research
Sept 2012 jconline.com: High-fat ketogenic diet reduces seizures in children
Sept 2012 m.phys.org: New model synapse could shed light on disorders such as epilepsy and anxiety
Sept 2012 guardian.co.uk: Researchers make progress toward predicting epilepsy seizures
Sept 2012 7thspace.com: The effects of glycemic control on seizures and seizure-induced excitotoxic cell death
Aug 2012 hopkinsmedicine.com: Medication offers hope to patients with frequent uncontrollable seizures
July 2012 thenational.ae: Microchip that detects an epileptic seizure
July 2012 scientificamerican.com: Implantable devices could detect and halt epileptic seizures
June 2012 medicalxpress.com: Epilepsy drugs increase risk of fractures and falls
June 2012 ScienceDaily.com: Could Roseola virus be behind epilepsy? Childhood virus infection linked to prolonged seizures with fever
June 2012 nytimes.com: New Epilepsy Tactic: Fight Inflammation
June 2012 ScienceDaily.com: Reverse Engineering Epilepsy’s ‘Miracle’ Diet
June 2012 6abc.com: Promising new epilepsy research
June 2012 nih.gov: SCN1A overview
June 2012 pubmed.gov: Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
June 2012 dailyrx.com: Seizure-free depends on first treatment
May 2012 genomeweb.com: UCB, Imperial College team up to identify epilepsy gene regulators
May 2012 MarketWatch.com: ETP launches first comprehensive epilepsy pipeline as a public resource identifying an estimated 80 product candidates in early- to late-stage development
May 2012 eurekalert.com: Pediatric epilepsy impacts sleep for the child and parents
May 2012 io9.com: Scientists switch mouse’s genes off and on with radio waves
May 2012 sacbee.com: Preventing autism after epilepsy
May 2012 psychcentral.com: Genetic link between epilepsy and psychosis?
May 2012 ScienceDaily.com: Molecule movements that make us think: ion channel’s voltage sensor can change its form
May 2012 dana.org: Ion channels and epilepsy: from molecule to mouse to medication
May 2012 medicalexpress.com: Overlooked nighttime spikes on EEGs may reflect an underlying brain injury
May 2012 Neurology.org: Autonomic changes with seizures correlate with postictal EEG suppression
Apr 2012 enewspf.com: Gauging seizures’ severity
Apr 2012 Market Watch: Upsher-Smith currently recruiting people with epilepsy to evaluate investigational rescue treatment for seizure clusters
Apr 2012 Market Watch: Lundbeck launches website to inspire and engage the Epilepsy Community – MarketWatch
Apr 2012 Science Daily: Key protein responsible for controlling nerve cell protection discovered
Apr 2012 Wall Street Journal: Treating epileptic seizures in kids by the clock
Apr 2012 Medscape: FDA puts 16 drugs on Watch List
Apr 2012 EpilepsyResearch.org: Scientists uncover epilepsy cause
Apr 2012 AES: Potential new role for a 19th century epilepsy drug
Apr 2012 DigitalJournal.com: Ontario Brain Institute leads the way in epilepsy research
Apr 2012 PubMed: Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
Apr 2012 AES: PAME (Partners Against Mortality in Epilepsy) Conference
Apr 2012 The JHU Gazette: New early warning system for seizures
Apr 2012 medicalexpress.com: Aging accelerates brain abnormalities in childhood onset epilepsy patients
Apr 2012 courant.com: Wesleyan research suggests stem cells show promise treating epilepsy
Mar 2012 Archives of Neurology: Progressive gait deterioration in adolescents with Dravet syndrome
Mar 2012 DSF: DSF Grantee receives NIH EUREKA Grant award
Mar 2012 NewsMedical.net: NeuroVista technology shows promise in detecting and predicting seizures
Mar 2012 esciencenew.com: New high definition fiber tracking reveals damage caused by traumatic brain injury
Mar 2012 Wesleyan.edu: Future stem cell-based therapies for treating epilepsy explored in 3 biology labs at Wesleyan
Feb 2012 suncoastpinellas.com: UF researchers make seizure discovery
Feb 2012 sfari.org: Rare epilepsy syndrome accompanied by autism
Feb 2012 UBC.com: New drugs show promise for preventing “absence seizures” in children
Feb 2012 redorbit.com: Gene mutation responsible for severe form of epilepsy identified
Feb 2012 deccanchronicle.com: Epilepsy kills if not treated, warns Dr. Solomon Moshe
Feb 2012 Epilepsy.com: Promising new epilepsy therapies featured at 2012 Epilepsy Pipeline Update Conference